EU gained’t take additional 300M doses of AstraZeneca, Johnson & Johnson: supply

2021-04-21 19:55:44

The European Union gained’t take up an additional 300 million doses of AstraZeneca and Johnson & Johnson COVID-19 vaccines that it has secured as choices beneath current contracts, a senior EU official informed Reuters.

The choice is the most recent signal Brussels is seeking to distance itself from AstraZeneca amid simmering tensions after the drugmaker slashed its supply targets attributable to manufacturing issues.

It’s also additional proof the bloc is sidelining vaccines which were linked with a really uncommon, however probably deadly facet impact, and is assured present suppliers — led by Pfizer/BioNTech — will ship sufficient doses to inoculate at the very least 70 per cent of EU adults by the tip of the summer time.

Just lately, the EU has sought to purchase extra pictures from Pfizer and its accomplice BioNTech, stepping up its bets on the messenger RNA (mRNA) know-how they use, versus the viral vector know-how utilized by AstraZeneca and J&J.

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The 27-nation bloc has a contract for a complete of 400 million doses with J&J, of which solely 200 million have already been ordered, and a separate contract with AstraZeneca for 400 million pictures, of which solely 300 million have been purchased.

“There isn’t any have to train the choices” for the additional doses, the official who’s instantly concerned in talks with vaccine makers mentioned.

EU governments are beneath strain to speed up vaccination applications, which have lagged these in Britain and the US attributable to provide delays and security issues, to assist tame a 3rd wave of infections.

A spokesman for the European Fee, which coordinates talks with vaccine makers, mentioned choices may be exercised at any time, however declined additional remark.


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The official, who requested to not be named as a result of the matter is confidential, mentioned discussions have been ongoing about additional provides for booster pictures and coronavirus variants, and it was untimely to rule AstraZeneca and J&J out of future contracts.

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However the know-how on which their pictures are based mostly is much less interesting than different vaccine platforms, the official mentioned. Final week, Italian newspaper La Stampa mentioned the EU wouldn’t renew contracts with the businesses once they expire.

Each vaccines have been linked to very uncommon instances of blood clots, which have led to non permanent suspensions of their rollout in Europe, though the EU medication regulator has concluded the advantages of each vaccines outweigh the dangers.

Each corporations have additionally had manufacturing issues, with AstraZeneca specifically slashing its EU provide targets by two thirds to 100 million doses by the tip of June, sparking fury in Brussels.

Learn extra:
300K Johnson & Johnson COVID-19 vaccines to reach in Canada final week of April

The EU official mentioned AstraZeneca’s provide issues had satisfied EU negotiators to not search the optionally available doses from the corporate. Underneath the contract, that possibility ought to have been exercised by early March, though the EU might have nonetheless tried to order extra doses after then.

A spokesman for AstraZeneca declined to remark.

The EU official added that, within the case of J&J, preliminary security issues about viral vector know-how had pushed negotiators to not search optionally available doses and may also forestall talks for a brand new contract.

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A spokeswoman for J&J declined to remark.


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At publication, there was no phrase on the place these doses undesirable by the EU would go, or whether or not Canada would search to acquire them and enhance its personal provide. International Information has reached out to Public Companies and Procurement Canada for remark.

Canada expects its long-awaited first cargo of 300,000 Johnson & Johnson vaccine doses over the last week of April. As for AstraZeneca, whereas there have been some setbacks, Canada expects to obtain practically 4.1 million doses by the tip of June with additional deliveries by way of the summer time.

The EU’s current COVID-19 vaccine contracts have been extensively criticized for being too lenient with corporations as a result of they set quarterly moderately than month-to-month supply targets, though different nations have carried out the identical.

Final week, the Fee mentioned it was beginning talks with Pfizer and BioNTech to purchase as much as 1.8 billion vaccine doses for the approaching years beneath a brand new contract with month-to-month targets, because it prepares for the attainable unfold of recent virus variants and potential waning safety from preliminary pictures.

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The EU supply mentioned the brand new contract with Pfizer and BioNTech was anticipated to fulfill a big share of the EU’s demand in 2022 and 2023.

Learn extra:
Johnson & Johnson vaccine protected regardless of attainable blood clot hyperlink, EU says

The bloc, with a inhabitants of practically 450 million, has already ordered 600 million Pfizer/BioNTech vaccines for this 12 months. It has additionally purchased 310 million doses from Moderna to be delivered this 12 months, and has an possibility to purchase one other 150 million doses subsequent 12 months. Moderna additionally makes use of mRNA know-how.

The EU additionally has contracts with CureVac and Sanofi, however neither of them has accomplished medical trials.

— with information from International Information






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